9.30 - 10.00 Registration
10.00 - 10.15 Opening of the course
10.15 - 10.30 Icebreaking for students
10.30 - 11.00 Introduction to course
11.00 - 11.30 Evidence-based medicine. What it is and what it isn't
11.30 - 12.00 Coffee-break
12.00 - 13.00 Basic sciences of EBM: Clinical epidemiology. Population. Patients. Normality. Tests.
13.00 - 13.30 Group work
13.30 - 14.30 Lunch
14.30 - 15.30 Basic Sciences of EBM: Biostatistics.
15.30 - 16.30 Group work
10.00 - 11.00 Introduction to EBM: EBM process. Clinically important question.
11.00 - 11.30 Groupwork
11.30 - 12.00 Coffee-break
12.00 - 13.00 Information search. General approach. Bibliographical databases. PubMed. MESH terms. Sesnsitive and specific search.
13.00 - 13.30 Reformulating clinical questions into PubMed search language. Groupwork
13.30 - 14.30 Lunch
14.30 - 15.30 Asssessment of the evidences. I. Natural history and prognosis articles. NNH
15.30 - 16.00 Assessment of the evidences II. Diagnosis
16.00 - 17.00 Groupwork
9.30 -16.00 Introduction to HTA, Including
11.30 - 12.00 Coffee-break
13.30 - 14.30 Lunch
16.00-17.00 Groupwork
Thirsday, November 29 (prof. E. Jonsson)
9.30 - 16.00 Introduction to economic evaluation, Including
11.30 - 12.00 Coffee-break
13.30 - 14.30 Lunch
16.00-17.00 Groupwork
9.30 - 10.30 International Collaboration in HTA (Yu.Shamova)
10.30 - 11.30 Development of EBM in Russia (E.Novichkova)
11.30 - 12.00 Coffee-break
12.00 - 12.30 Resource center at MMA. Projects (E.Novichkova)
12.30 - 13.00 Development of EBM at MAPS (T.Dubikaitis)
13.00-13.30 Groupwork
13.30 - 14.30 Lunch
14.30 - 16.00 Asssessment of the evidences III. Etiology
16.00 - 17.00 Groupwork
10.00 - 11.30 EBM tools. Introduction to systematic reviews. Prof. V.Vlasov
11.30 - 12.00 Coffee-break
12.00 - 13.30 Asssessment of the evidences IV. Therapy. NNT. S.Varshavsky
13.30 - 14.30 Lunch
14.30 - 15.00 Cochrane collaboration. Goals and tasks. V.Vlasov and S. Varshavsky
15.00 - 16.00 Doing own research. Planning of experiment. Error types. Number of study participants.
16.00 - 17.00 Groupwork
10.00 -11.30 Introduction to meta-analysis. Data collection & graphical methods
11.30 - 12.30 Coffee - break
12.30 - 13.30 Statistical methods of meta-analysis I. Common effect size estimation.
13.30 - 14.30 Lunch
14.30 - 16.00 Statistical methods of meta-analysis II. Heterogenity. Subgroup analysis. SAS system for meta-analysis
16.00 - 17.00 Groupwork
10.00 - 11.30 Introduction to clinical decision analysis. Game theory. Utility. Utility elicitation.
11.30 - 12.00 Coffee-break
12.00 - 13.30 Clinical Decsion Analysis I. Classical methods: Decision trees, threshold proability, NNT/NNH
13.30 - 14.30 Lunch
14.30 - 16.00 Multiattribute Decision Analysis Models and Time-dependent course: Analytical Hierarchical Process. Markov modelling. Estimation of QALY from Markov modes. Computerzed analysis. Decision analysis for health managers.
16.00 - 17.00 Groupwork
10.00 - 11.30 Introduction to scientific writing T.Dubikaitis
11.30 - 12.30 Coffee break
12.30 - 13.30 Scientific writing, cntd...
13.30 - 14.30 Lunch
14.30 - 16.00 Ethical problems in EBM/HTA
16.00 - 17.00 Groupwork
10.00 - 11.30 Clinical guidelines. Grading of evidences. Prof. O.Kuznetsova
11.30 - 12.00 Coffee-break
12.00 - 13.30 Exam
13.30 - 14.30 Lunch
14.30 - 16.00 Roundtable discussion of EBM and HTA. Discussion of the course. What do we need to implement EBM?